66758
Turmeric, Grapes, Apple Compounds ‘Starve’ Cancer Cells
Turmeric, Grapes, Apple Compounds ‘Starve’ Cancer Cells

Turmeric, Grapes, Apple Compounds ‘Starve’ Cancer Cells

Turmeric, Grapes, Apple Compounds ‘Starve’ Cancer Cells

What do turmeric, apples, and grapes have in common? According to a new study, they could hold the key to preventing and treating one of the most common cancers in the United States.
Researchers have identified a number of natural compounds that have the potential to “starve” prostate cancer tumors and shrink them.
Compounds present in turmeric, red grapes, and apple peel appear to have the strongest effect, particularly in combination.
Study co-author Stefano Tiziani, of the Department of Nutritional Sciences and the Dell Pediatric Research Institute at the University of Texas at Austin, and colleagues recently reported their findings in the journal Precision Oncology.
After skin cancer, prostate cancer is the most common cancer among men in the US. According to the American Cancer Society, there will be 161,360 new cases of prostate cancer diagnosed this year, and around 26,730 men will die from the disease.
Previous studies have identified a number of compounds, particularly found in plant-based foods that have the potential to reduce the risk of prostate cancer.
For this latest study, Tiziani and colleagues used a novel, high-throughput screening technique to test 142 natural compounds, with the aim of identifying those that are most effective for halting the growth of prostate cancer cells.
The compounds were tested on prostate cancer cells derived from mice and humans, individually and in combination.
The team identified three compounds that were most effective for halting prostate cancer cell growth: curcumin, the bright yellow compound in turmeric; ursolic acid, found in apple peel; and resveratrol, found in red grapes and berries.

 Tested in Mouse Models
These three compounds were then tested in mouse models of prostate cancer.
Researchers found that when ursolic acid was combined with either curcumin or resveratrol, the natural compounds prevented the uptake of glutamine by prostate cancer cells, which prevented tumor growth in the mice.
Glutamine is an amino acid that prostate cancer cells need in order to grow, so preventing its uptake effectively “starves” the cancer cells to death.
What is more, because ursolic acid, curcumin, and resveratrol are natural compounds, they did not cause any toxic effects in the mice.
However, researchers note that the concentrations of each of the three compounds were higher than that which is normally consumed through diet. Still, the team believes that the findings show promise for a natural strategy to prevent and treat prostate cancer.
“These nutrients have potential anti-cancer properties and are readily available. We only need to increase concentration beyond levels found in a healthy diet for an effect on prostate cancer cells,” said Tiziani.

Short URL : https://goo.gl/urMUwT
  1. https://goo.gl/mDL7EE
  • https://goo.gl/1D6K5S
  • https://goo.gl/7bP2jT
  • https://goo.gl/fPMifP
  • https://goo.gl/UjtnRw

You can also read ...

Iran Preparing UNESCO Dossier for Iranian Railroads-Photo Jean Marc Fryburg
Cultural heritage officials, in cooperation with the Islamic...
Four Hajj Pilgrims Die
Four Iranian hajj pilgrims (three men and one woman) have lost...
Math, Chemistry Olympiad Winners
Iran has topped the 18th math and 10th chemistry international...
Three Killed  in Bus Crash
Three people were killed and 35 were injured when a bus...
Obesity and related health risks are responsible for 17% of deaths among Iranians.
Obesity is prevalent in low-income households in Tehran, and...
Sistan-Baluchestan is looking to overhaul its image for domestic and foreign travelers.
Work has begun on developing four coastal tourism resorts in...
Restricting the availability of jobs to EU nationals and access to social security will deter many from making the journey.
European nationals will still be able to pass freely without...
Iran Reviewing Rural Tourism Potentials
Iranian authorities will review the tourism potentials of 1,...

Add new comment

Read our comment policy before posting your viewpoints

Image CAPTCHA
Enter the characters shown in the image.

Trending

Googleplus