Unidentified gunmen shot dead five people in Saudi Arabia's Eastern Province late on Monday evening, the state news agency reported.
Nine people were wounded in the attack in al-Dalwah town in al-Ahsa district, Reuters quoted a police spokesman as saying.
"As a group of citizens was leaving a building...three masked men opened fire at them with machine guns and pistols," the spokesman said, adding that the incident was under investigation.
It gave no further details. Al-Ahsa is one of the two main centers of minority Shia Muslims in Sunni-ruled Saudi Arabia, along with the district of Qatif.
The shooting comes as Shia Muslims worldwide are holding ceremonies marking Ashoura, a 10-day event commemorating the death of the Prophet Muhammad's grandson Imam Hussein in battle 1,300 years ago.
Qatif and Al-Ahsa have historically been the focal point of anti-government demonstrations in Saudi Arabia.
Shias in the kingdom say they face discrimination in seeking educational opportunities or government employment and that they are referred to disparagingly in text books and by some Sunni officials and state-funded clerics.
They also complain of restrictions on setting up places of worship and marking Shia holidays, and say that Qatif and al-Ahsa receive less state funding than Sunni communities of equivalent size.
The Saudi government denies allegations of discrimination.
A government census in 2001 said there were about a million Saudi Shias. But US diplomats in a 2008 embassy cable released by WikiLeaks estimated they represent up to 12 percent of the total Saudi population, which now numbers 20 million.