The TSE's main index TEDPIX lost 3,311.67 points or 0.25% on Monday to end trade at 1,318,714.22.
About 3.92 billion shares worth 23.97 trillion rials ($82.67 million) changed hands at TSE for the day.
Trading at TSE and over-the-counter Iran Fara Bourse starts on Saturday and ends Wednesday.
Sobhan Pharmaceutical Group Company was the big winner as its shares went up 4.9% to 8,350 rials per share.
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