‘Genetic Link’ Between Creativity & Schizophrenia
Art And Culture

‘Genetic Link’ Between Creativity & Schizophrenia

Post-impressionist painter Vincent van Gogh was believed to suffer from schizophrenia and musician Kurt Cobain was diagnosed with bipolar disorder. The incidence of such conditions among creative individuals has led researchers to speculate there may be a link between creativity and psychiatric illness. Now, a new study finds this link may be partly genetic.
Study author Robert Power, of the Institute of Psychiatry, Psychology and Neuroscience (IoPPN) at King’s College, London in the UK, and colleagues published their findings in the journal Nature Neuroscience.
Creativity is defined by researchers as “novel approaches requiring cognitive processes that are different from prevailing modes of thought or expression.”
Such approaches are normally adopted by people who have visionary professions or hobbies, such as artists, musicians, actors, dancers and writers. But does creativity increase an individual’s risk of mental illness?
Past research has found that mental illnesses - particularly bipolar disorder - are more common among people with relatives who have creative professions. However, researchers have been unable to identify the mechanisms underlying this association. For their study, Power and colleagues wanted to find out.
“For most psychiatric disorders little is known about the underlying biological pathways that lead to illness,” says Power. “An idea that has gained credibility is that these disorders reflect extremes of the normal spectrum of human behavior, rather than a distinct psychiatric illness.”
“By knowing which healthy behaviors, such as creativity, share their biology with psychiatric illnesses,” he adds, “we gain a better understanding of the thought processes that lead a person to become ill and how the brain might be going wrong.”
With the help of researchers from deCODE Genetics - a biopharmaceutical company in Iceland - the team was able to analyze data for 86,292 people from Iceland’s general population.
The researchers calculated genetic risk scores for schizophrenia and bipolar disorder for each individual, and they identified the creativity of each person - determined by their profession or enrollment in national artistic societies of dancers, actors, musicians, writers and visual artists.
The team found that individuals whose profession was a painter, musician, writer or dancer were 25% more likely to carry gene variants related to bipolar or schizophrenia than those in less creative jobs, such as manual laborers and farmers.


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