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US Attack on IS Prison Kills 57

A suspected US-led coalition air raid on a prison run by the self-styled Islamic State terrorist group in eastern Syria has killed at least 57 people, according to a monitoring group.

The Syrian Observatory for Human Rights said on Tuesday that most of the fatalities in the town of al-Mayadeen in Deir Az Zor Province were civilian inmates, Aljazeera reported.

At least 15 IS fighters were also killed in the raid, the UK-based monitor, which tracks developments in Syria's long-running conflict via a network of contacts on the ground, said.

Al-Ikhbariya, a Syrian state-run TV station, also cited its Deir Az Zor correspondent as saying coalition fighter jets had destroyed a building in al-Mayadeen used as a prison by IS to hold a "large number of civilians".

An activist-run media outlet in Deir Az Zor also reported the hit, which it said took place at dawn on Monday.

The US Central Command confirmed to AP on Tuesday that it struck IS facilities in al-Mayadeen on June 25 and 26, but made no direct reference to the alleged IS prison.

CENTCOM said it will assess the allegations that civilian prisoners were killed and it would publish the results of its assessment in its monthly civilian casualty report.

It said the Mayadeen mission was "meticulously planned and executed to reduce the risk ... to non-combatants".

The US-led coalition is supporting an alliance of Kurdish and Arab fighters in their assault on IS in its de-facto capital of Raqqa in northern Syria.

"The removal of these facilities disrupts IS's ability to facilitate and provoke terrorist attacks against the coalition, our partner forces and in our homelands," Colonel Joe Scrocca, coalition director of public affairs, said in an email to Reuters.